自体角膜缘干细胞移植联合丝裂霉素治疗翼状胬肉30例分析

Auto-corneal limbus stem cell transplantation combined with Mitomycin C (MMC) for the treatment of pterygium:an analysis of 30 cases

目的:观察自体角膜缘干细胞移植联合丝裂霉素C治疗翼状胬肉的临床疗效。方法:对29例30只眼翼状胬肉患者,行翼状胬肉切除,同时术中应用0.02%丝裂霉素C联合自体角膜缘干细胞移植,术后随访胬肉复发情况。结果:术后随访6～18个月,角膜创面愈合良好,治愈28例,复发2例2眼。结论:翼状胬肉切除联合术中应用自体角膜缘干细胞移植联合丝裂霉素治疗翼状胬肉能有效降低胬肉术后复发率。

Objective ：To observe clinical efficacy of auto-corneal limbus stem cell transplantation combined with MitomycinC for the treatment of pterygium. Methods ：Auto-corneal limbus stem cell transplantation combined with 0.02% MitomycinC after excision were performed in 29 patients （30eyes）with pterygium.The recurrency rate was ob- served over a 6-18 months follow-up period.Results：All patients＇ cornea healed well.Recurrence of pterygium was observed only in 2eyes.Conclusion：Auto-corneal limbus stem cell transplantation combined with MMC is an effective therapy for pterygium.h can obviosly reduce the postoperative recurrent rate of pterygium.