不同剂量潘生丁心电图负荷试验诊断冠心病的临床评价

Clinical evaluation of dipyridamole electrocardiogram stress test of different dose for diagnosing CHD

目的 :比较大剂量与普通剂量潘生丁心电图负荷试验诊断冠心病的价值。方法 :冠心病患者 94例分为 2组(各 47例 ) ,分别采用大剂量 (0 .85 m g/ kg)和普通剂量 (0 .75 mg/ kg)潘生丁进行了潘生丁心电图负荷试验。结果 :1大剂量组 :阳性 38例 (80 .9% ) ,副反应 2 9例 (6 1.7% ) ;2普通剂量组 :总阳性 43例 (91.5 % ) ,其中症状阳性 39例 (83.0 % ) ,ECG阳性 37例 (78.7% ) ,副反应 2 1例 (5 5 .3% )。两组阳性符合率和副反应发生率 ,均无显著差异 (P>0 .0 5 )。结论 :潘生丁心电图负荷试验中潘生丁的剂量超过 0 .75 mg/ kg无益。

AIM:To compare diagnosing value of coronary heart disease (CHD) between dipyridamole(Dp) electrocardiogram stress test of large dose Dp and general dose Dp. METHODS:94 patients with CHD were divided into two groups (47 cases,respectively),large dose group (0.85 mg/kg) and general dose group (0.75 mg/kg) were performed Dp electrocardiogram stress test. RESULTS:①large dose group,positive 38 cases (80.9%);②general dose group,general positive 43 cases (91.5%),symptom positive 39 cases (83.0%),ECG positive 37 cases (78.7%), side effect 21 cases(55.3%). No significent difference between positive correspondent rate and side effective rate of two group (P>0.05). CONCLUSION:Dose of Dp in Dp electrocardiogram stress test more than 0.75 mg/kg is not benifit.