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人副肠孤病毒3型研究进展 被引量:1

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摘要 人副肠孤病毒(humanparechoviruses,HPeVs)为单股正链RNA病毒,包含多个不同的基因型别,是一类较为常见的可致呼吸系统、消化系统和中枢神经系统等感染并引发多种相应的临床症状和体征的病原体。人副肠孤病毒3型(humanparechovirus3,HPeV.3)是其中一种新近发现的基因型别,首次由Ito等…于2004年报道,检出于13本1例患有短暂性麻痹的1岁患儿的粪便标本,具有与其他HPeV基因型别明显不同的流行病学特征和细胞异嗜性。近年来越来越多的研究表明该病毒型别与一些严重的儿童疾患的发生密切相关,如败血症样临床表现、脑炎与脑膜脑炎等中枢神经系统的感染与损伤,突发性婴幼儿死亡等。
作者 郭英 钱渊
出处 《中华儿科杂志》 CAS CSCD 北大核心 2013年第2期111-114,共4页 Chinese Journal of Pediatrics
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参考文献49

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二级参考文献9

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