摘要
青光眼是全球常见且不可逆的严重致盲眼病,其视功能损害的病理基础是视网膜神经节细胞的进行性死亡和神经纤维的丢失。神经节细胞死亡主要是通过细胞凋亡的方式进行的,其在本质上与大多数神经系统疾病的病理生理特征包括氧化应激与能量障碍是一致的。而线粒体在细胞凋亡中起着主开关的作用。
Glaucoma is common and is a leading cause of irreversible blindness worldwide. The pathological foundation of visual function damage is the death of retinal ganglion cells and the loss of nerve fibers. Ganglion cell death is mainly through cell apoptosis. Its pathophysiological features are the same as with most of the diseases of the nervous system including oxidative stress and isehemia. The mitochondrion is a vital intraeellular organelle for retinal cell function and survival.
出处
《中华眼视光学与视觉科学杂志》
CAS
2013年第2期126-128,共3页
Chinese Journal Of Optometry Ophthalmology And Visual Science