摘要
目的探讨左乙拉西坦治疗小儿癫痫的疗效及不良反应。方法对116例小儿癫痫患者进行LEV治疗,采用开放性自身对照随访观察,比较治疗前后癫痫发作次数、频率、不良反应等,评价其疗效及安全性。结果治疗后病情得到控制者76例(65.52%),显效23例(19.83%),总有效率为85.34%;治疗后,各类型小儿癫痫的发作次数均有显著减少(P<0.05);不良反应较少(19.83%),治疗2～6周后消失。结论左乙拉西坦治疗小儿癫痫临床疗效显著,是一种安全有效的广谱抗癫痫药。
Objective To investigate the efficacy and adverse effects of treatment for pediatric epilepsy by levetiracetam（LEV）. Methods 116 cases of pediatric epilepsy treated by LEV,using of self-control follow-up observation of openness,the number of seizures and the frequency of adverse reactions were compared and the efficacy and safety was evaluated. Results 76 cases（65.52%）were controlled,23 cases（19.83%）were effective and the total efficiency was 85.34%.Seizure frequency was significantly reduced （P 〈 0.05）. Conclusion The clinical effect of LEV treatment of pediatric epilepsy is significant and it is a safe and effective broad-spectrum anti-epileptic drugs.
出处
《中国医药科学》
2013年第5期90-91,共2页
China Medicine And Pharmacy
关键词
左乙拉西坦
小儿癫痫
不良反应
Levetiracetam
Pediatric epilepsy
Clinical features
Adverse reactions
