2012年上半年某院细菌耐药情况分析与药学解读

Analysis and interpretation of pharmacy of bacterial drug resistance of one hospital in the first half of 2012

目的分析医院细菌耐药特点,并从药学的视角进行解读,为临床合理应用抗菌药物提供依据。方法调取医院2012年上半年细菌耐药性监测资料并进行统计分析。结果 2012年1～6月的阳性标本有3260例。其中革兰阳性细菌878株,占26.93%;革兰阴性细菌2176株,占66.75%;真菌204株,占6.26%。前5位细菌是:大肠埃希菌、铜绿假单胞菌、鲍曼不动杆菌、金黄色葡萄球菌、屎肠球菌。结论合理的药学解读有助于规范临床合理用药,规范的抗菌药物应用能减缓细菌耐药趋势。

Objective To analyze the characteristics of drug resistance of bacteria to antibiotics in our hospital, and from the perspective of pharmacy,to provide clinical basis for rational use of antimicrobial agents. Methods Accessed the bacterial resistance surveillance data of the hospital in the first half of 2012 and statistical analysis. Results From January 2012 to June,there were 878（26.93%）strains of gram positive bacterium,2176（66.75%） of gram-negative bacterium;204（6.26%） strains of fungus.The top 5 bacteria： escherichia coli;pseudomonas aeruginosa;acinetobacter baumannii;staphylococcus aureus;enterococcus faecium. Conclusion Reasonable pharmaceutical analysis can help standard clinical rational drug use,and standardized antimicrobial application can slow down the bacteria resistance trend.