高压氧联合奥拉西坦治疗血管性痴呆36例疗效分析

Curative effect analysis of hyperbaric oxygen associated with oxiracetam on 36 cases of vascular dementia

目的探讨高压氧联合奥拉西坦治疗血管性痴呆的临床疗效。方法将72例血管性痴呆患者随机分为观察组和对照组(各36例),观察组应用高压氧联合奥拉西坦治疗,对照组单用奥拉西坦治疗。结果两组患者治疗后MMSE评分均明显高于同组治疗前(P<0.05),但观察组治疗后MMSE评分明显高于对照组治疗后(P<0.05);两组治疗后ADL评分均明显低于同组治疗前(P<0.05),但观察组治疗后ADL评分明显低于对照组治疗后(P<0.05)。结论高压氧联合奥拉西坦治疗血管性痴呆具有较好疗效,对患者的智力障碍和日常活动能力能够起到显著改善作用,值得推广。

Objective To probe into the clinical effect of hyperbaric oxygen associated with oxiracetam. Methods 72 vascular dementia patients were divided into observation group and control group（n=36）. Hyperbaric oxygen associated with oxiracetam was applied to observation group,and oxiraeetam was applied to control group. Results MMSE scores of patients of two groups after treatment were higher than those before treatment （P 〈 0.05）. However,MMSE score of observation after treatment was obviously higher than that of control group after treatment （P 〈 0.05）.ADL scores of two groups were obviously higher than those of two groups before treatment.But ADL score of observation group after treatment was obviously lower than that of control group after treatment（P 〈 0.05）. Conclusion Hyperbaric oxygen associated with oxiracetam has better curative effect, and can have significant improving function on intellectual disturbance and daily activities of patients. Therefore,it is worthy of promotion.