胸腺肽联合抗生素治疗老年慢性支气管炎急性发作期的疗效观察

Effect of thymosin combined with antibiotics in the treatment of elderly with acute exacerbations of chronic bronchitis

目的对胸腺肽联合抗生素治疗老年慢性支气管炎急性发作期的临床效果进行探讨。方法将医院2011年3月～2012年3月收治的老年慢性支气管炎急性发作期患者40例,随机分成两组,两组患者均采用常规对症支持治疗,5～7d为一个疗程,治疗组在常规治疗的基础上给予胸腺肽80mg/d静脉滴注,1个疗程后对两组临床疗效进行比较分析。结果对照组显效5例(25.00%),好转9例(45.00%),无效6例(30.00%),总有效率为70.00%;治疗组显效12例(60.00%),好转7例(35.00%),无效1例(5.00%),总有效率为95.00%;两组患者的总有效率差异有统计学意义(P<0.05)。结论治疗组临床疗效明显优于对照组,该法临床疗效确切,效果显著,值得临床推广应用。

Objective The effect of thymosin Combined with antibiotic therapy in the elderly with acute exacerbations of chronic bronchitis clinical effect were discussed. Methods 40 cases of elderly patients with acute exacerbation of chronic bronchitis were selected as observation object from March 2011 to March 2012,they were randomly divided into two groups.Two groups of patients were treated by routine treatment,5-7 d as a course,the patients in conventional treatment group were treated with thymosin 80 mg/d intravenous infusion,after 1 courses of treatment,the clinical outcomes of the two groups were compared. Results In the control group, 5 cases （25%） were markedly improved,improved efficiency in 9 cases （45%）,invalid in 6 cases （30%）, the total efficiency was 70%.In the treatment group, 12 cases were markedly improved（60%）, improved efficiency in 7 cases （35%）,invalid in 1 cases （5.00%）,the total efficiency was 95.00%.The total efficiency of two groups had significant difference （P 〈 0.05）. Conclusion Clinical effect of treatment group was better than the control group,it is worthy of clinical application.