653例解脲脲原体和人型支原体的检测与结果分析

Detection and results analysis on 653 cases of ureaplasma urealyticum and mycoplasma hominis

目的了解非淋菌性尿道炎患者支原体感染及耐药情况,泌尿生殖道支原体的感染情况及耐药现状,指导临床合理用药。方法支原体的鉴定和药敏采用珠海丽珠试剂有限公司解脲脲原体和人型支原体培养鉴定药敏试剂盒。结果在653份标本中检出支原体阳性279例,检出率为42.7%;解脲脲原体感染的220例,人型支原体感染的59例,解脲脲原体占阳性标本78.5%;支原体感染以中青年为主(21～40岁),占阳性标本的92.1%,对支原体敏感的主要药物依次为强力霉素、克拉霉素、交沙霉素;而支原体对氧氟沙星耐药率最高49.5%。结论解脲脲原体是本地非淋菌性尿道炎感染主要病原体,应重视支原体的感染及其耐药性,合理用药。

Objective To understand the mycoplasma infection and drug resistance conditions of patients with non- gonocoecal urethritis （NGU） and the mycoplasma infection and drug resistance status in urinary and reproductive tracts in order to guide clinical medication. Methods The ureaplasma urealyticum and mycoplasma hominis culture,identification and drug susceptibility kit produced by Zhuhai Lizhu Reagents Co.,Ltd.were used for mycoplasma identification and drug susceptibility. Results Of the 653 specimens,279 cases were mycoplasma-positive,with the detection rate of 42.7%. Ureaplasma urealyticum （Uu） infection was found in 220 cases and mycoplasma hominis infection was found in 59 cases （Mh）~with Uu accounting for 78.5% of the positive samples. Mycoplasma infection mainly occurred in young and middle-aged people （21-40 years old）, accounting for 92.1% of the positive samples. Mycoplasma was mainly sensitive to doxycycline, clarithromycin and josamyein and its resistance rate for ofloxacin was the highest 49.5%. Conclusion Uu is the main pathogen of local NGU infection and therefore mycoplasma infection and its drug resistance should he emphasized for the purpose of rational drug use.