化学发光免疫法检测前列腺特异性抗原的临床应用

Clinical application of chemiluminescence immunoassay in testing PSA

目的探讨化学发光免疫法检测前列腺特异抗原在医学中的应用情况。方法把需检测对象分为3个组,分别为良性前列腺增生组、前列腺癌患组和正常对照组;采用化学发光免疫法分别检测三组的t-PSA的含量。结果良性前列腺增生组与前列腺癌组中的t-PSA含量要明显高于对照组。三个组之间比较存在着显著的差异。而前列腺癌患者的t-PSA值显著大于良性前列腺增生组(P<0.01)。结论采用化学发光法检测t-PSA达到了理性的效果,为前列腺癌患者的临床诊断提供了一定的依据。

Objective To discuss the clinical application of chemiluminescence immunoassay in testing PSA. Methods The tested objects were divided into three groups as BPH group,prostate cancer group and normal control group.Content Of t-PSA of the three groups were tested by chemiluminescence immunoassay. Results Content of t-PSA of BPH group and prostate cancer group was obviously higher than control group.There were significant differences between the three groups. The content of t-PSA of prostate cancer group was significantly larger than BPH group （P 〈 0.01）. Conclusion Testing t-PSA by chemiluminescence immunoassay has reached a rational effect, and it provides some basis for the diagnosis of prostate cancer.