高血压脑出血后二次脑损伤相关因素对预后的影响

The effect of prognosis value in Hypertensive intracerebral hemorrhage and secondary brain insult

目的探讨二次脑损伤(secondary brain insult,SBI)高危因素对高血压脑出血(Hypertensive intrace-rebral hemorrhage,HIH)患者预后的影响。方法对182例高血压脑出血(HIH)合并SBI与无合并SBI患者的临床资料进行回顾性分析。结果按Glasgow预后评分(GOS),SBI组恢复良好65例(56.0%)、中度残废6例(5.2%)、严重残废7例(6.0%)、植物生存3例(2.6%)、死亡35例(30.2%)。合并一种SBI因素较两种以上SBI因素预后好。无SBI组恢复良好57例(86.4%)、中度残废2例(3.0%)、死亡7例(10.6%)。两组预后比较差异有统计学意义(P<0.05)。结论 SBI加重原发性脑损伤,关系到高血压脑出血患者的预后,应积极预防SBI和干预治疗。

Objective To discuss the effect of SBI on prognosis in patients with HIH trauma. Methods Retrospec- tive analysis were employed in the analysis of data from 182 patients with HIH trauma, which were complicated or uncompli- cated with SBI. Results According to ctlasgow outcome scale（ GOS）, aAmong of SBI group ,65 （56.0%）cases with good recovery,6（ 5.2% ） moderate disability, 7 （ 6.0% ） severe disability, 3 （ 2.6% ） persistent vegetative state, 35 （ 30.2% ） death; ,Aamong the other cases without SBI, 57 （ 86.4% ） cases with good recovery, 2 （ 3. 0% ） moderate disability, 7 （ 10.6% ） death, the difference between two groups was significant （ P 〈 0.05 ）. Conclusion SBI aceeleratinereased sig- nificantly the primarily brain injury significantly and were relatedion to the prognosis of patients with HIH severe craniocere- bral tranma, so it is essential important to obviate actively and take intervention therapy.