新乡地区反复自发性流产夫妇的病因学调查

Etiological study of frequentation spontaneous abortions.

36 4对反复自发性流产夫妇中共检出染色体异常者 41例 ,占受检总数的 5 .6 3% ,共有 32种异常核型 ,其中染色体数目异常 11例 ,结构异常 30例 ,15例具有家族性遗传倾向 ,17例为新突变者。TORCH试验 ,女性组ToAbIgM、CMVAbIgM ,与对照组有显著性差异 (P <0 .0 5 )。 11对夫妇ABO、Rh血型不合 ,抗体滴度 >1:32。 3例女性具有生殖系统器质性病变。提示染色体异常、感染、血型不合、器质性病变与反复自发性流产相关。

Of 364 couples with frequentative spontaneous abortions,41 were detected the presence of chromosome abnormalities (5.61%).Among 32 abnormal karyotypes,there were 11 cases with numerical abnormality and 30 cases with structural aberrations.15 cases had a tendency of family heredity,17 cases were neomorpyh.TORCH test showed a statistically significant differences in contrast with the control group P<0.05 in TOAb IgM、CMVAb IgM of the woman group.11 coupled were patients with blood group incompatibility in ABO,Rh,their antibody concentration >1:32.3 female patients suffered from organic lesions of reproductive system.It showed that chromosome abnormality,infection blood group incompatibility and organic lesions were connected with frequentative spontaneous abortions.