重庆地区34家医院2009-2011年头孢菌素类药利用分析

Analysis of the Utilization of Cephalosporins in 34 Hospitals in Chongqing Area from 2009 to 2011

目的:了解重庆地区医院头孢菌素类药的应用情况和变化趋势,为临床合理用药及科学管理提供参考。方法:调查重庆地区34家医院2009-2011年头孢菌素类药的销售金额、用药频度(DDDs)、日均费用(DDC)等,并进行统计、分析。结果:3年来,该地区医院头孢菌素类药销售金额平均占全部药品总销售金额的10.09%,2010年较2009年增长23.35%,而2011年较2010年降低13.23%。第3代头孢菌素销售金额占头孢菌素类药销售金额的49.04%;第4代头孢菌素占9.28%,呈逐年下降趋势。第3代头孢菌素的DDDs占总DDDs的46.42%。第4代头孢菌素的DDC为163.89元,位居首位。结论:该地区医院头孢菌素应用以第3代头孢菌素居多。为延缓细菌耐药的产生,临床医师应根据药敏试验结果选择用药,以便规范管理头孢菌素类药的应用。

OBJECTIVE： To understand the application and trends of cephalosporins in hospitals from Chongqing area, and to provide reference for rational drug use and scientific management in the clinic. METHODS： The utilization of cephalosporins in 34 hospitals from Chongqing area during 2009-2011 was analyzed statistically in respects of consumption sum, DDDs and DDC. RE- SULTS： In the last three years, the consumption sum of cephalosporins accounted for 10.09% of total drug consumption sum, in- creasing by 23.35% in 2010 compared with 2009, but decreasing by 13.23% in 2011 compared with 2010. The consumption sum of the 3rd-generation cephalosporins accounted for 49.04% of the cephalosporins; however, that of the 4th-generation cephalospo- rins accounted for 9.28% of the cephalosporins, declining year by year. DDDs of the 3rd-generation cephalosporins was 46.42% of total DDDs. DDC of the 4th-generation cephalosporins was 163.89 yuan, ranking the first place. CONCLUSIONS： The 3rd-genera- tion cephalosporins are majority in Chongqing area. Physicians should select drugs based on the results of drug sensitivity test so as to standardize the utilization of cephalosporins.