施氏假单胞菌的临床分布及其耐药性研究

Clinical Distribution and Drug Resistance of Pseudomonas stutzeri

目的:研究施氏假单胞菌的临床分布情况及其耐药性。方法:收集1994年6月至2010年11月福建医科大学附属泉州市第一医院门诊及病房分离出的23株施氏假单胞菌的资料,分析其临床分布情况,采用琼脂扩散法检测其耐药性。结果:23株施氏假单胞菌在各个年度、临床科室中均呈散在分布,标本分布以痰为主(15株,占65.2%);对庆大霉素、阿米卡星、多黏菌素B、头孢曲松、环丙沙星、头孢他啶、哌拉西林、亚胺培南的耐药率分别为56.5%、52.2%、0、39.1%、26.1%、8.7%、26.1%、4.3%。结论:施氏假单胞菌对氨基糖苷类较为耐药,对多黏菌素B、头孢曲松、环丙沙星、哌拉西林、头孢他啶、亚胺培南较为敏感。

OBJECTIVE： To study the clinical distribution and drug resistance of Pseudomonas stutzeri. MPSIHUDS： 23 strains of P stuzeri isolated from outpatient department and wards of quanzhou municipal first hospital affiliated to fujian medical universi- ty during Jun. 1994--Nov. 2010 were collected and analyzed in respect of clinical distribution. Bacteria resistance of P stuzeri was detected using agar diffusion method. RESULTS： 23 strains of P stuzeri distributed diffusely in clinical departments during Jun. 1994-Dec. 2010; isolated samples were mainly sputum （15 strains, 65.2% ）; drug resistances to gentamicin, amikacin, polymyx- in B, cephalosporin aspergillus, ciprofloxacin, ceftazidime, piperacillin and imipenem were 56.5%, 52.2%, 0, 39.1%, 26.1%, 8.7 %, 26.1%, 4.3%, respectively. CONCLUSIONS： P. stuzeri is resistant to aminoglycoside, and sensitive to polymyxin B, ceph- alosporin aspergillus, ciprofloxacin, piperacillin, ceftazidime and imipenem.