药学服务对慢性阻塞性肺疾病稳定期患者用药依从性的影响

Effects of Pharmaceutical Care on Drug Compliance of Patients with Chronic Obstructive Pulmonary Disease in Stable Phase

目的:探究药学服务计划的制订与实施对慢性阻塞性肺疾病(COPD)防治的影响。方法:将2011年6月至2012年6月在我院呼吸科诊断为COPD稳定期的150例患者随机分为两组,各75例。试验组按照药学服务计划对患者的用药情况进行干预,包括门诊用药咨询、电话查访、疾病及药学知识普及讲座;对照组不施加任何干预措施。6个月后,统计两组患者对药物的了解情况、药品不良反应发生情况及急性发作情况。结果:随访调查结果显示,试验组患者对药物适应证、副作用、药物用法及注意事项的了解程度高于对照组;试验组患者药品不良反应发生率(22.67%)明显低于对照组(65.33%),用药依从性好的比率(89.3%)高于对照组(80%)。结论:实施药学服务计划可明显提高COPD稳定期患者的用药依从性。

OBJECTIVE ： To discuss the effects of pharmaceutical care plan on prevention and treatment of chronic obstructive pulmonary disease （COPD）. METHODS： 150 patients diagnosed as COPD in stable phase in respiration department of our hospital from Jun. 2011 --Jun. 2012 were randomized into 2 groups with 75 cases in each group. Drug use of experimental group was inter- vened according to pharmaceutical care plan, including outpatient medication consultation, telephone investigation, disease and pharmaceutical knowledge popularization lecture; control group did not received any intervention. After 6 months, patients＇ knowl- edge about medication, occurrence of ADR and acute attack were analyzed in 2 groups statistically. RESULTS： Results of fol- low-up survey showed that patients＇ understanding degree of drug indications, side effects, drug usage and precautions in experi- mental group were higher than in control group; the incidence of ADR in experimental group （22.67%） was obviously lower than in control group （65.33%）, and the proportion of good drug compliance（89.3% ）was higher than in control group（80.0% ）. CON- CLUSIONS： Pharmaceutical care plan can improve drug compliance of patients significantly with COPD in stable phase.