黄芪提取液对小白鼠离体子宫收缩活动的影响

Astragalus Extract to the Little White Rat in Vitro The Influence of Uterine Contraction Activities

目的:探讨黄芪提取液对小白鼠离体子宫收缩活动的影响。方法:以生理盐水组作对照,采用离体器官灌流的方法,分别滴加生理盐水,不同浓度黄芪提取液(1 g.ml-1、2 g.ml-1、3 g.ml-1)各0.2 ml,2单位缩宫素,观察小白鼠离体子宫收缩活动曲线下面积的变化。结果:滴加生理盐水后对离体子宫收缩活动曲线下面积的影响不显著,而滴加黄芪提取液(1 g.ml-1,2 g.ml-1、3 g.ml-1)后,离体子宫收缩曲线下面积增加明显(P﹤0.05),缩宫素组子宫收缩曲线下面积增加更显著(P﹤0.01),子宫收缩曲线下面积增加均具有统计学意义。结论:黄芪提取液有增强离体子宫收缩活动的功效。

Objective：To investigate astragalus extract to the little white rat in vitro the influence of uterine contraction activities. Methods：To physiological saline as a control group, the in vitro organ perfusion method, respectively drop and physiological saline, different concentration astragalus extract （ 1 g·ml^-1 , 2 g·ml^-1 , 3 g·ml^-1 ） , oxytocin each 0. 2 ml, observation of mice in vitro uterine contraction activities of the area under the concentration - time curve changes. Results ： Drop and physiological saline after the in vitro uterine contraction activities of the influence of the area under the concentration - time curve was not significant, but that drop and astragalus extract （ 1 g·ml^-1, 2 g·ml^-1, 3g·ml^-1 ） , in vitro uterine contraction area under curve significantly increased （ P 〈 0. 05 ） , oxytocin group of uterine contraction curve area increase more significant （ P 〈 0. 01 ）, uterine contraction curve area increase which will have a statistics meaning. Conclusions：Astragalus extract have enhanced in vitro uterine contraction activities of the efficacy.