儿童及青少年肥胖的干预

Intervention for obesity in children and adolescents

近20年来，儿童及青少年肥胖的发生率在世界范围内均明显升高，肥胖相关的危害更为引人瞩目。目前公认的儿童及青少年肥胖干预方法主要通过调整生活方式，包括饮食控制、增加运动、心理认知行为干预等。大量的证据表明，上述措施有确切的短期减重效果，然而长期效果尚未明确。即使彻底调整生活方式，仍有一部分人群减重效果不理想，因此，学者们致力于开辟有效安全的新途径，包括药物、手术，以及肥胖疫苗，以期控制儿童、青少年肥胖及其相关疾病的发生。

In the past two decades, it has witnessed a significant increase of the prevalence of obesity and the comorbidities in children and adolescents all over the world. So far, the most accepted intervention of obesity in children and adolescents is the lifestyle modification, including dietary control, increasing physical activity and psychosocial and cognitive intervention. It has been proved that lifestyle modification does have short-term effects on weight management, while the long-term effects remain unclear. Although with intensive lifestyle modification, there are still a number of people without promising result. Therefore, researchers are making great effort to develop new strategies, for instance, medication, surgery and vaccine, to better control the prevalence of obesity and its complication in children and adolescents.