摘要
研究了BVDV2/JZ05-1和BVDV1/JZ05-3二价弱毒活疫苗的制备工艺。通过对BVDV2/JZ05-1和BVDV1/JZ05-3疫苗毒传代培养测定毒价后,试制出5批毒价分别是105.4TCID50/mL和105.6TCID50/mL的BVDV二价弱毒活疫苗,经检验符合试验设计要求。
The aim of this study was to explore the preparation technique of divalent attenuated virus live vaccine of bovine viral diarrhea virus 2/JZ05- 1 (BVDV2/JZ05- 1) and BVDV1/JZ05- 3. BVDV2/JZ05- 1 and BVDV1/JZ05- 3 were continuously cultivated in cell culture. The poison titor was examined.5 groups of divalent attenuated BVDV live vaccine were produced. The poison prices were 10^(5.4)TCID50/mL and 10^(5.6)TCID50/mL,respectively. The vaccines were examined and was within the range of the test design requirement.
出处
《特产研究》
2013年第1期1-2,18,共3页
Special Wild Economic Animal and Plant Research
基金
吉林省科技发展计划(20100219)
关键词
牛病毒性腹泻
病毒
活疫苗
bovine viral diarrhea
virus
live vaccine