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盐酸贝那普利对原发性轻中度高血压患者心电图的影响 被引量:7

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摘要 目的探讨盐酸贝那普利对原发性轻中度高血压患者心电图的影响。方法选取原发性轻中度高血压患者186例随机分为2组,对照组93例采用苯磺酸氨氯地平5 mg/次晨起口服,1次/d,观察组93例采用盐酸贝那普利10 mg/次晨起口服,1次/d,2组疗程均为6个月,比较2组患者治疗前后血压、心率、心电图情况。结果治疗后,对照组舒张压、收缩压均明显下降且有显著性差异(P均<0.05),观察组舒张压、收缩压、心率均明显下降且有显著性差异(P均<0.05)。观察组舒张压、收缩压均明显低于对照组,有显著性差异(P均<0.05)。观察组IVST、LVD、LVPWT、LVMI均明显下降而E/A比值明显升高(P均<0.05),与对照组比较均有显著性差异(P<0.05)。2组不良反应发生率比较无显著性差异(P>0.05)。结论盐酸贝那普利用于治疗原发性轻中度高血压具有显著的临床效果,不仅可以明显降压,还能有效改善患者的心功能,尤其是左心室的舒张功能。
作者 余建家
出处 《现代中西医结合杂志》 CAS 2013年第11期1187-1188,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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