194例妇科患者支原体检测及药敏分析

Mycoplasma detection and sensitivity analysis in 194 gynecological patients

目的探讨妇科门诊患者中生殖道支原体感染的状况及药敏情况。方法回顾分析2011年7月至2012年8月来该院妇科门诊就诊患者的194例宫颈分泌物支原体培养及药敏结果。结果在送检的194例宫颈分泌物标本中检出为阳性的患者有101例,占52.1%。在这101例患者中有71例患者为单项解脲脲原体感染,占送检人数的36.6%,占阳性患者的70.3%;17例患者为单项人型支原体感染,占送检人数的8.8%,占阳性患者的16.8%;13例患者为混合感染解脲和人型支原体占送检人数的6.7%,占阳性患者的12.9%。通过对12种抗菌药物进行的敏感试验分析,其中交沙霉素和美满霉素敏感率最高,均为95.0%,环丙沙星最低(5.0%);耐药率环丙沙星最高(78.2%),交沙霉素和强力霉素最低,均为2.0%。结论对支原体引起的妇科生殖道疾病进行治疗选择正确的抗菌药物至关重要。

Objective To investigate the status and susceptibility of genital Mycoplasma infection in gyneco- logical outpatients. Methods A retrospective analysis of Mycoplasma culture and drug susceptibility test of cervical secretions in 194 gynecology clinic patients from July 2011 to August 2012 in our hospital was done. Results In the submission of the 194 cervical secretion samples, 101 cases were detected positive,accounting for 52.1%. 71 patients had ureaplasma urealytieum infection, the detection rate of 36.6%,accounting for 70.3% of the positive patients. 17 patients were with single Mycoplas.ma hominis infection, the detection rate of 8.8 %, accounted for 16.8% of the pos- itive patients. 13 patients were with mixed infection of ureaplasma urealyticum and Mycoplasma hominis, the detection rate of 6.7%, accounting for 12.9 % of the positive patients. In sensitivity test of 12 antimicrobial agents, susceptibility rates of josamycin and minocycline were both 95.0% ,and that of ciprofloxacin was a minimum of 5.0%. The re sistance rate of eiprofloxacin was 78.2%, and that of josamycin and Minocin were both a minimum of 2.0 %. Conclusion Right choice of antibacterial drugs for treatment of gynecological reproductive tract disease caused by Mycoplasma is essential.