腺苷脱氨酶及C-反应蛋白检测对胸腔积液鉴别诊断的临床意义

Clinical significance of the united detection of ADA and CRP in the diagnosis of pleural effusion

目的探讨腺苷脱氨酶(ADA)及C-反应蛋白(CRP)检测对诊断结核性与癌性胸腔积液的价值。方法对临床确诊的93例结核性和56例癌性患者胸腔积液分别进行ADA及CRP的检测,并对结果进行比较分析。结果结核性患者胸腔积液ADA和CRP的水平含量分别为(51±7)U/L、(27.0±8.4)mg/L;癌性患者胸腔积液ADA和CRP的水平含量分别为(19±4)U/L、(14.0±5.7)mg/L,两者比较差异均有统计学意义(P<0.05)。结论 ADA及CRP检测在鉴别结核性和癌性胸腔积液方面具有较好的实用价值和临床意义。

Objective To investigate the value of the united detection of adenosine deaminase （ADA） and C- reactive protein （CRP） in the diagnosis of tuberculous and malignant pleural effusion. Methods The ADA and CRP of pleural effusion were detected in 93 cases of tuberculosis and 56 cases of cancer patients,and the results was ana- lyzed comparatively. Results The ADA and CRP levels of pleural effusion in tuberculous patients were （51±7）U/L and （27±8.4） mg/L, respectively. The ADA and CRP levels of pleural effusion in cancer patients were （ 19 ± 4） U/L and （14 ± 5.7）mg/L, respectively. The ADA and CRP levels of pleural effusion in tuberculous patients were signifi cantly higher than that in cancer patients （P〈0.05）. Conclusion The ADA and CRP levels of pleural effusion in tuberculous patients were higher than that in cancer patients. The united detection of ADA and CRP has good practical value and clinical significance in the diagnosis of tuberculous and malignant pleural effusion.