养阴活血法治疗肾病综合征高凝状态的临床观察

Nourishing yin and promoting blood circulation in treating nephrotic syndrome and hypercoagulable state of clinical observation

目的观察养阴活血法对肾病综合征高凝状态临床疗效。方法 40例高凝状态肾病综合征患者随机分为治疗组和对照组,对照组给予激素加西药潘生丁口服,治疗组在此基础上加用中药加味二至丸。结果治疗4周后,治疗组PLT、CHOL、FIB、LDL-C改变的程度大于对照组,差异有统计意义(P<0.05)。结论养阴活血法有助于减轻高凝状态肾病综合征患者的高凝状态和高脂血症。

Objective To evaluate the clinical effects of prevention of Hypercoagulable state on nephritic syndrome with the therapy of nourishing yin and promoting blood circulation. Methods 40 cases of patients with nephritic syndrome were randomly divided into treatment group and control group. The same basic treatment was given for all the patients. At the same time, The treatment group was given the decoction of Modified Erzhi pill, while the control group was given Persantine. The blood lipids, coagulation were compared before treatment and after 4 weeks treatment. Results Compared period of before and after treatment, the triglyceride, blood cholesterol, Low - density lipoprotein, platelet all decreased than that of before treat- ment in both group. The difference was statistically significant （P 〈 0. 05 ） . The changes of the blood cholesterol, Low-density lipoprotein, platelet and serum fibrinogen of the treatment group were more significantly than that of the control group, the differ- ence was statistically significant （P 〈 0. 05 ） . Conclusion The therapy of nourishing yin and promoting blood circulation can improve hyperlipidemia and hypercoagulation state in PNS patient.