糖尿病对冠心病药物洗脱支架择期植入前后中医证型分布及演变规律影响的研究

Study on Changes of Traditional Chinese Medicine Syndrome in CHD with Diabetes Around Intervention Treatment with DES in Selected Date

目的:探讨糖尿病对冠心病药物洗脱支架植入前后中医证型演变规律的影响。方法:对两家三甲医院62例术前诊断为冠心病合糖尿病且符合其它各项标准的病例,按术前、术后24小时、术后1周、术后1月、术后3月、术后6月完成中医病史的采集及证型的辨别,最后进行整理、统计和分析。结果:冠心病合并糖尿病患者介入术后24小时至术后3月气虚证明显增多(P<0.05或P<0.01),阴虚证在术后1月明显增多(P<0.05),所有病理阶段痰浊证均明显增多(P<0.01),气滞证在术后1周明显增多(P<0.01),血瘀证在术后1月、术后6月时明显增多(P<0.05)。结论:糖尿病主要对CHD药物洗脱支架择期植入前后的痰浊证、气虚证,对血瘀、气滞证。

Objective：To explore the distribution and changing rule around intervention treatment with DES implanted of Traditional Chinese Medicine（TCM） syndromes in CHD with diabetes,and the influence of syndrome on account of PCI.Methods：TCM syndromes of 62 patients of CHD implanted DES with diabetes were analyzed according to six different times around PCI：before,after 24 hours,after 1 week,after 1 month,after 3 months,after 6 months.Results：CHD with diabetes,the counts of phlegm-turbid syndrome had a significant increase at every times（P0.01）,Yin deficiency had a increase after 1 month of PCI（P0.05）,After a week of PCI,Qi stagnation syndrome had a increase（P0.05）,Qi deficiency had a increase too after 24 hours to 3 month（P0.05）,Blood stasis syndrome had a increase at 1 month and 6 month after PCI.Conclusion：It has certain effects to phlegm-turbid syndrome,blood stasis syndrome,Qi stagnation syndrome,Qi deficiency syndrome and Yin deficiency in CHD with diabetes by PCI with DES.