老年人下丘脑脚区脑白质解剖学及影像学观察

An anatomic and imaging observation on old people brain white matter of inferior thalamic peduncle

目的采用DTI技术及Klingler解剖技术,对60岁以上老年人下丘脑脚区脑白质解剖结构进行相关研究。方法①10例成人尸体颅脑标本采用Klingle解剖技术,对下丘脑脚区脑白质进行逐层分离,观察并进行数据测量。②对10名健康志愿者采用DTI成像技术进行脑白质纤维束成像,同时应用DTT方法对下丘脑脚区进行重建。结果采用Klingler解剖技术可清晰显示下丘脑脚区脑白质的结构及位置。采用磁共振成像中的DTI技术能够直观而清晰的显示下丘脑脚区脑白质纤维束。结论运用Klingler解剖技术和DTI成像技术可直观、清晰地显示下丘脑脚区脑白质纤维束的结构及位置。下丘脑脚区脑白质基本结构相同,但部分脑白质的大小、形态却存在个体性差异。通过DTI技术可以较好地对下丘脑脚区脑白质进行临床诊断及准确定位。

Objective The cerebral white matter of the inferior thalamic peduncle of old adults was observed to provide scientific basis for the clinical diagnosis and accurate location of brain diseases, using Klingler fiber dissection technique and DTI technique. Methods （1）Ten adult human brains were frozen and dissected following the Klingler technique to observe and measure the white mat- ter structure of inferior thalamic peduncle. （2）Ten healthy volunteers were chosen to take the imaging of white matter by the DTI tech- nique and reconstruct the white matter by the DTT technique. Results （1）The anatomical structure and positions of cerebral white mat- ter, including the external capsule, the arcuate fasciculus, the uncinate fasciculus , the inferior occipitofrontal could be clearly demon- strated with the Klingler anatomy technique. （2）The main brain white matter structure of inferior thalamic peduncle all mentioned above could be shown clearly with the DTI technique. Conclusion （1）The Klingler anatomy technique and the DTI technique based on the basis of anatomy could clearly display the structure and position of the cerebral white matter fiber of inferior thalamic peduncle. （2）The cerebral white matter of inferior thalamic peduncle has a common basic con-structure with some individual differences in the size and shape. （3）DTI technique could be well applied to the clinical diagnosis and accurate location of the cerebral white matter of inferior tha- lamic peduncle.