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糖皮质激素的基础及其在儿童肾病综合征中的临床应用 被引量:10

The use of glucocorticoid in children with nephrotic syndrome
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摘要 糖皮质激素是临床应用最广泛的药物之一,其在肾病综合征中更是得到了广泛应用。该文重点从糖皮质激素的基础如分类、临床剂量区分、作用机制、应用的基本原则、肾上腺轴被抑制与否的判断、注意事项及在肾病综合征中的临床应用等方面进行概述。 Glucocorticoid is one of the widely used drugs in clinic, especially in nephrotic syndrome. This paper mainly summarizes its use in nephrotic syndrome in clinic, focusing on its classification, different dosage, mechanisms, basic principles of application, the inhibition of adrenal axis and precautions.
作者 夏正坤
出处 《国际儿科学杂志》 2013年第2期191-193,共3页 International Journal of Pediatrics
基金 国家自然科学基金资助项目(81270800)
关键词 糖皮质激素 儿童 肾病综合征 Glucociorticoid Children Nephrotic syndrome
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参考文献20

  • 1Cupps TR, Fauci AS. Corticosteroid-mediated immunoregulation in man. Immunol Rev, 1982,65 : 133-155.
  • 2Rook GA. Glucocorticoids and immune function. Baillieres Best Pract Res Clin Endocrinol Metab, 1999,13 : 567 -581.
  • 3Baschant U,Tuckermann J. The role of the glucocorticoid receptor in inflammation and immunity. J Steroid Biochem Mol Biol,2010, 120(2-3) :69-75.
  • 4Meijsing SH, Pufall MA, So AY, et al. Yamamoto, DNA bind-ing site sequence directs glucocorticoid receptor structure and activity. Science,2009,324 (5925) :407-410.
  • 5Szilagyi K, Podracka L, Franke NE, et al. A new link between steroid resistance, glucocorticoid receptor and nuclear factor kappa B 1965 in idiopathic nephrotic syndrome. Neuroendocfinol Lett, 2009,30 (5) : 629-636.
  • 6Yan K, Kudo A, Himo H, et al. Subeellular location of glucocorticoid receptor protein in the human kidney glomerulus. Kidney Int, 1999, 56:65-73.
  • 7Kunugi H, Hori H, Numakawa T, et al. The hypothalamic-pituitary- adrenal axis and depressive disorder: recent progress. Nihon Shinkei Seishin Yakurigaku Zasshi, 2012,32 ( 4 ) :203 -209.
  • 8Belda X,Daviu N, Nadal R, et al. Acute stress-induced sensitization of the pituitary-adrenal response to heterotypic stressors:independ- ence of glucocorticoid release and activation of CRH1 receptors. Horm Behav,2012,62(4) :515-524.
  • 9Koskinies O, Vilska J, Rapola J, et al. Long-term outcome of primaru nephrotic syndrome. Arch Dis Child,1987,57:544-548.
  • 10Tarshish P,Tobin JN,Bwenstein J, et al. Prognostic significance of the early course of minimal change nephrotic syndrome: report of the International Study of Kidney Disease in Children. J Am Soc Nephrol, 1997,8 ( 5 ) : 769 -779.

二级参考文献76

  • 1孙嫱,沈颖.Meta分析评价环磷酰胺对儿童肾病综合征的治疗作用[J].中华儿科杂志,2006,44(3):199-201. 被引量:20
  • 2莫樱,陈述枚.肾病综合征频复发及激素依赖的治疗[J].中国实用儿科杂志,2007,22(6):412-416. 被引量:12
  • 3Filler G, Young E, Geier P, et al. Is there really an increase in non-minimal change nephrotic syndrome in children? Am J Kidney Dis ,2003,42 : 1107-1113.
  • 4Eddy AA,Symons JM. Nephrotic syndrome in childhood. Lancet, 2003.362:629-639.
  • 5Wong W. Idiopathic nephrotic syndrome in New Zealand children, demographic, clinical features, initial management and outcome after twelve-month follow-up: results of a three-year national surveillance study. J Pedia Child Health,2007,43:337-341.
  • 6易著文.小儿临床肾脏病学//易著文,钟巧.肾病综合征.北京:人民卫生出版社,1998:346-361.
  • 7Koskinies O, Vilska J, Rapola J, et al. Long-term outcome of primary nephrotic syndrome. Arch Dis Child, 1987,57:544-548.
  • 8Tarshish P, Tobin JN, Bwenstein J,et al. Prognostic significance of the early course of minimal change nephrotic syndrome:report of the International Study of Kidney Disease in Children. J Am Soc Nephrol, 1997,8:769-779.
  • 9American College of Cardiology/European Society of Cardiology Clinical Expert Consensus Document on Hypertrophic Cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. Eur Heart J ,2003,24 : 1965-1991.
  • 10Schrier RW. Disease of the kidney and urinary tract. 8th ed. Philadelphia: Lippincott Williams and Wilkins, 2007: 1585- 1672.

共引文献1869

同被引文献121

  • 1李丽英,王海燕,朱世乐,潘缉圣.黄芪当归对肾病综合征鼠肝白蛋白的表达作用[J].中华医学杂志,1995,75(5):276-279. 被引量:187
  • 2吴俊,梅长林.活性维生素D在肾脏病领域的应用进展[J].实用药物与临床,2005,8(5):40-43. 被引量:8
  • 3王永钧,鲁盈.原发性肾病综合征的诊断、辨证分型及疗效评定(试行方案)[J].上海中医药杂志,2006,40(10):51-52. 被引量:153
  • 4Koskinies O,Vilska J,Rapola J,et al.Long-term outcome of primary nephrotic syndrome[J].Arch Dis Child,1982,57(7):544-548.
  • 5Tarshish P,Tobin J N,Bwenstein J,et al.Prognostic significance of the early course of minimal change nephrotic syndrome:report of the Internatinal Study of Kidney Disease in Children[J].J Am Soc Nep hrol,1997,8(5):769-779.
  • 6Schrier R W.Disease of the kidney and urinary tract[M].8th.Philadelphia:Lippincott Williams and Wilkins,2007:1585-1672.
  • 7Zhao M,Chen X,Chen Y,et al.Clinical observations of mycophenolate mofetil therapy in refractory primary nephrotic syndrome[J].Nep hrology,2003,8(3):105-109.
  • 8Hiraoka M,Tsukahara H,Matsubara K,et al.A randomized study of two long-course prednisolone regimens for nephrotic syndrome in children[J].Am J Kid Dis,2003,41(6):1155-1162.
  • 9Hodson E M,Willis N S,Craig J C.Corticosteroid therapy for nephrotic syndrome in children (review)[J].Cochrane Database Syst Rev,2007,4:CD001533.
  • 10Antignac C. Genetic models: clues for understanding the pathogenesis of idiopathic nephrotic syndrome [J]. J Clin Invest, 2002 , 109 ( 4 ) : 447449.

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