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颅骨Paget病1例并文献复习

CASE REPORT OF SKULL ON PAGET'S DISEASE AND ITS REVIEW
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摘要 目的通过对1例Paget病的分析,探讨该病的病因、诊断、影像表现及治疗方法。方法结合患者的影像及临床资料,同时复习相关文献报道进行总结。结果患者骨破坏及骨增生并存,血碱性磷酸酶水平明显升高,临床主要表现为受累骨的疼痛和畸形,二磷酸盐是首选的治疗药物,病变严重时需手术。结论 Paget病罕见,颅骨及全身大部分骨骼均可累及,有典型的影像学和临床特征,确诊需进行全面的检查,目前此病尚不能治愈。 Objective To explore etiology, diagnosis, imaging findings and treatment methods by analyzing of one case of Paget's disease. Methods A summary report was finished combined reviews, images and clin- ical data of the patient. Results The coexistence phenomena of bone destruction and bone hyperplasia in the patient, serum alkaline phosphatase levels were significantly increased, pain and deformity of the affected bone were major clinical manifestations. Bisphosphonate was choice drugs for treatment, and surgery was required for serious cases. Coneluslon Paget disease with typical imaging and clinical feature is rare and in- curable, and most of the bones of the skull and body can be involved. A comprehensive examination is es- sential to confirme the disease.
作者 张芳
出处 《中国煤炭工业医学杂志》 2013年第3期513-514,共2页 Chinese Journal of Coal Industry Medicine
关键词 PAGET病 颅骨病变 畸形性骨炎 Paget's disease l The skull lesions, Osteitis deformans
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参考文献5

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