种植体周围袋中中间普氏菌的检测及临床意义

A one-year study on the changes of prevotella intermedia in subgingival plaque of dental implant

目的:研究一年内人工种植牙龈下中间普氏菌的变化情况,为种植体的定期维护提供理论基础。方法:临床选取38名种植患者的46枚种植体,并将其分成A、B两组。A组是种植修复后1年时探诊种植牙周有出血的种植体20枚,B组是无探诊出血的种植体26枚。检查记录种植修复后1个月,修复后3个月,修复后6个月,修复后12个月四个时段,入选种植牙的菌斑指数(PL)I,牙龈指数(G)I,探诊深度(PD),X-线骨吸收值;采用中间普氏菌的选择性培养基对种植体龈下菌斑标本进行了分离培养。结果:横向比较A、B两组之间中间普氏菌计数、牙龈指数(G)I、探诊深度(PD)有统计学差异,其余检测指标无统计学差别。修复后3月时,A、B两组之间中间普氏菌计数值有统计学差异。纵向比较,随时间延长,A、B两组种植牙周中间普氏菌检出量不断增加,1月到3月时增加的趋势最为明显,到6个月左右趋于稳定。其统计值在1个月和3个月比较有统计学差异,但在6个月和12个月比较无统计学差异。各临床指标和X-线指标随时间的变化无统计学意义。结论:在临床工作中,应注意加强修复后3月时种植患者的口腔维护,防止种植体周围炎的发生,提高种植成功率。

Objective： To study the changes of Prevotella intermedia of the implants within one year. Meth- ods： Collect 46 implants in 38 patients, divided them into two groups. Group A contained 20 implants which probed bleeding after 1 year restoration. Group B contained 26 which probed no blood. Evaluate, in the four stages of one month, 3 months, 6 months and 12 months after restoration, their Plaque Index （PLI）, Gingival Index （GI）, Probing Depth （PD） and X-ray bone absorption. S were cultured separately by the selective medium of Prevotella intermedia. ubgingival plaque samples Results： The horizontalcomparison of the group A and B shows that the value of Prevotella intermedia count, gingival index （GI）, probing depth （PD） is statistically different from group B. Other tested indexes show no statistic difference. 3 month after restoration, the value of Prevotella intermedia in group A is significantly dif- ferent from group B. In the longitudinal comparison of the two group, the value of Prevotella intermedia is increasing as time went on. From the 1st to the 3rd month, the value increases most obviously and by the 6th month, becomes stable. The value of Prevotella intermedia is statistically different between the 1st and the 3rd month, and show no statistical difference between the 6th and 12th month. Other tested indexes show no statistic difference. Conclusions： Patients with implants should be guided to do cleansing and maintenance in oral cavity after 3 months restoration, so as to prevent peri-implantitis and increase success rate of implants.