生物医学领域本体的构建、评估与应用

Construction,Assessment and Applications of Biomedical Ontologies

介绍了本体的概念和基本特点,总结了领域本体的一般构建流程和评估方法,并举例说明了生物医学领域本体在生物学对象注释、富集分析、数据整合、数据库构建、图书馆建设、文本挖掘等方面的实际应用情况,整理了目前常用的生物医学领域本体数据库、本体描述语言和本体编辑软件,最后探讨了目前生物医学领域本体研究中普遍存在的问题和该领域未来的发展方向.

This review first introduces the concept and essential characteristics of ontology,and presents the general construction and evaluation methodology of domain ontology.Several examples illustrate the applications of biomedical ontologies in biological data annotation,enrichment analysis,data integration,database and library construction,text mining and other aspects.The current commonly used biomedical ontology databases,ontology description languages and editing softwares are also summarized.Finally,we discuss some common problems in the establishment and application of biomedical ontologies,and provide a few suggestions for future developments of this filed.