太原市健康人腰椎骨密度研究

Bone mineral density in lumbar spines of healthy people in Taiyuan,China

我院从 1995～ 1998年 ,通过健康检查对 1551名太原地区健康人群进行腰椎骨密度( BMD)研究 ,其中男性 517人 ,女性 10 34人 ,在不同年龄段中发现骨矿峰值在 30～ 39岁 ,两性一致 ,男性保持 2 0年 ,女性 10年后骨矿含量随年龄增加而减少。女性 60岁以后 BMD降低 2 1.66% ,而男性仅3.54% ,其中 L1降低达 18.87% ,L2 与 L2 -4 降低的幅度 ,女性一致 ,男性则有显著差异。本研究认为 L2 -4男性降低的幅度不显著与腰椎退行性病变、骨质增生、骨赘形成、韧带及组织钙化有关 ,而 L1则少受此影响。同时在腰椎压缩性骨折患者中 L1最为多见均提示 L1降低的重要性 ,因而提出女性患者应用 L2 -4BMD作为骨质疏松诊断 ,是与国内外诊断的金指标一致 ,而对男性要重视 L1降低的临床意义。无论采用“局限性”骨质疏松 。

From 1995 to 1998,1551 healthy persons including 517 men and 1034 women in Taiyuan area were observed for bone mineral density of lumbar vertebrae. The results indicate that the peak values of bone mineral density in lumbar vertebrae of both men and women occur in the 30-39 year old groups,from then on the peak values last for 20 years in men and 10 years in women,then the bone mineral densities of both sexes begin to lower with increasing age. After 60 years of age, the bone mineral density (L 2-4 ) in women is reduced by 21.66%,but that in men only by 3.54% (L 2-4 ). Comparing the reduction extent of bone density in L 1 with that in L 2-4 ,there is no difference in women but there is a significant difference in men. The retardation of bone density (in L 2-4 ) reduction in men is chiefly owing to the degenerative changes in lumbar vertebrae, for example,osteoproliferation, formation of osteophyte and calcification in soft tissue or in ligament. Bone density reduction of L 1 in men is much more obvious (18.87%) than that of L 2-4 in men (3.54%),and compression fracture is often seen in the first lumbar vertebra among the other lumbar vertebrae. The result revealed the great significance of bone mineral density of L 1 in diagnosing osteoporosis in men.