摘要
目的:运用宝石CT能谱成像技术探索甲状腺乳头状癌能谱曲线斜率值特征,并与正常甲状腺组织及结节性甲状腺肿的能谱曲线斜率值比较。方法:收集北京大学深圳医院2011年8月至2012年2月接受甲状腺能谱CT检查并经手术病理证实的甲状腺病变患者34例,使用GE公司宝石CT(GE Discovery CT750 HD CT)GSI模式扫描,图像采集后用GSI Viewer浏览器处理,获得病灶及正常甲状腺组织能谱曲线,分析能谱曲线并计算出斜率值K(40keV与100keV两点间斜率值)。采用Wilcoxon秩和检验进行统计学分析。结果:手术病理结果:甲状腺乳头状癌16例、结节性甲状腺肿18例。甲状腺乳头状癌与结节性甲状腺肿及正常甲状腺组织能谱曲线斜率值K差异均具有统计学意义(P值均小于0.05)。结论:甲状腺乳头状癌的能谱曲线斜率与正常甲状腺组织及结节性甲状腺肿具有显著性差异,K值能够明显地反映这一差异,此将为甲状腺乳头状癌诊断提供一种新的方法。
Purpose： Gemstone spectral imaging（GSI） has an ability to show spectral HU curve. The purpose of this study was to explore the characteristics of spectral HU curve on papillary carcinoma of thyroid, and to compare the different values of spectral HU curve slope of normal thyroid and nodular lesions with gemstone spectral CT. Methods： Thirty-four cases of thyroid nodule that were all confirmed with surgical pathology in Peking University Shenzhen Hospital from August 2011 to February 2012 were collected. GSI scans were acquired on a Discovery CT750 HD scanner. Image processing was performed on GSI Viewer browser to get the energy spectrum curves of normal thyroid tissue and lesions. K （slope between 40 keV and 100 keV） slope values were calculated by analyzing these curves. Statistical analysis was processed with Wilcoxon rank test. Results： Surgical pathology results showed that there were 16 cases of papillary carcinoma of thyroid and 18 cases of nodular goiter, statistial differences of spectral HU curve slope values （K） were found among thyroid papillary carcinoma, goiter and normal thyroid parts. Conclusion： There are significant differences in the spectral HU curve slope values among papillary carcinoma of thyroid, normal thyroid and nodular goiter, Kvalue could clearly reflect the difference, which might provide a new method to diagnose and differentiate papillary carcinoma of thyroid from normal thyroid and nodular goiter.
出处
《中国医学计算机成像杂志》
CSCD
北大核心
2013年第1期7-10,共4页
Chinese Computed Medical Imaging
