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动态监测血清降钙素原水平对脓毒症诊断的临床价值 被引量:5

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摘要 目的探讨动态监测血清降钙素原(PCT)水平对判断脓毒症的严重程度及预后的临床意义。方法以本院ICU病房2008年1月至2010年12月收治的111例脓毒症患者为研究对象,在诊断为脓毒症的第1、3、5、7天分别抽取静脉血,进行血清PCT水平的动态监测,并同时检测CRP、WBC和记录APACHEⅡ评分。结果 111例患者中存活92例(存活组),死亡19例(死亡组)。死亡组血清PCT水平第3、5、7天分别是(16.2±5.2)、(14.3±3.6)、(13.9±2.7)ng/mL明显高于存活组的(9.4±2.3)、(3.8±1.2)、(2.2±0.7)ng/mL,差异有统计学意义(P<0.05)。同时,死亡组的CRP、WBC、APACHEⅡ评分均明显高于存活组,并呈持续上升趋势,而存活组上述指标呈持续下降趋势。结论脓毒症的严重程度和预后与患者血清PCT水平明显相关,动态监测PCT水平有助于判断脓毒症的严重程度和预后。
作者 廖扬 石玉玲
出处 《国际检验医学杂志》 CAS 2013年第6期736-738,共3页 International Journal of Laboratory Medicine
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参考文献12

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