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深圳西部2005~2011年献血者血液复检结果分析 被引量:3

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摘要 目的探讨血清胱抑素C(CysC)对狼疮性肾炎(LN)患者早期肾功能损害监测的意义。方法检测100例系统性红斑狼疮患者的24h尿蛋白,根据尿蛋白结果将患者血清分为两组,阳性组和阴性组,对照组为30例健康体检者,三组分别检测CREA,UREA,URIC,CysC,进行组间比较。结果 UREA、URIC、CREA水平在正常体检组与尿蛋白阴性组之间差异无统计学意义,尿蛋白阳性组水平明显高于阴性组和健康体检组;CysC水平在尿蛋白阳性组与阴性组均高于健康体检组,且尿蛋白阳性组CysC水平明显高于阴性组。血清CysC水平异常率明显高于其他的血清标志物,提示其能更早的发现肾功能的改变。结论血清CysC水平能更好的监测狼疮性肾病患者的肾功能,并且能更早发现患者的肾功能改变,是早期诊断狼疮性肾炎比较好的血清标志物。
出处 《国际检验医学杂志》 CAS 2013年第6期750-752,共3页 International Journal of Laboratory Medicine
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二级参考文献28

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