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盐酸右美托咪定应用于无痛人流术麻醉的临床观察 被引量:5

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摘要 目的:观察盐酸右美托咪定应用于无痛人流术麻醉的可行性及临床效果。方法:选择ASA I~II级拟行无痛人流术的早期妊娠病人60例,随机、双盲分为两组(每组30例)进行研究。对照组采用生理盐水2ml+1%丙泊酚20ml+阿托品3ml(0.3mg);观察组采用盐酸右美托咪定2ml(8ug)+1%丙泊酚20ml+阿托品3ml(0.3mg)全凭静脉注射麻醉,分别记录两组病人入室后HR、MAP和SpO2;以及丙泊酚的用量、注射痛和苏醒时间。结果:与对照组相比,观察组病人HR、丙泊酚的用量、注射痛和苏醒时间均有显著降低(P<0.05或P<0.01);MAP和SpO2无显著性差异(P>0.05)。结论:盐酸右美托咪定应用于无痛人流术麻醉安全可行且明显减轻了丙泊酚注射痛,在减少了丙泊酚平均用量的同时也缩短了病人的平均苏醒时间,降低了病人围术期呼吸循环抑制的风险,值得临床推广。
作者 徐家丽 冯丹
出处 《数理医药学杂志》 2013年第2期210-211,共2页 Journal of Mathematical Medicine
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