三种静脉麻醉方法在紧急气管插管中的临床研究

Clinical study of three kinds of anesthesiainduction before tracheal intubation

目的比较三种气管插管前麻醉诱导方法的优缺点,探讨气管插管麻醉诱导的最佳方法。方法将我院急救中心2008年9月～2011年7月期间收治的需紧急气管插管患者240例,随机分为3组,司可林+芬太尼组、咪唑安定+芬太尼组、丙泊酚组。比较3组患者插管成功率、并发症及插管前、插管时、插管后1、3、5min的收缩压、舒张压、心率、氧饱和度。最后行成本效益分析。结果丙泊酚组患者一次性插管成功率最高、无明显心血管反应、呼吸抑制等并发症最少,成本效益比最高。结论丙泊酚用于气管插管是优于其他两种气管插管的麻醉诱导方式。

Objective To compare threes kinds of anesthesiainductionbefore trachea intubation and find the optimal method of anesthesiainduction.Methods A total of 240 patients in emergency department needed urgent tracheal intubation were randomized into 3 groups（scoline＋fentanyl group,midazolaem group,propofol group） in a period between September 2008 and July 2011.Comapare initialintubationsuccessrates,complications change of oxygen saturation（spo2）.Collect data of thesystolicpressure（SBP）,diastolic pressure（DBP）,heartrateandrespirationratebefore,during and after intubation of 1min,3min,5min.Analysis cost effective.Results The propofol group had the highest initialintubationsuccessrate and the minimal complications of respiratory depression and cardiovascular effects,the most cost effective.Conclusion Propofolis the best method of anesthesia induction before trachea intubation.