银杏达膜对急性脑梗死患者神经功能恢复及脑可塑性的作用

Role of Ginkgo dipyridolum on neurological function recovery and brain plasticity in patients with acute cerebral infarction

目的评价银杏达膜(杏丁注射液)治疗急性脑梗死患者的临床疗效。方法将50例急性脑梗死患者随机分为观察组和对照组各25例。对照组采用常规疗法。观察组在接受与对照组相同治疗的基础上,加用杏丁注射液静脉滴注,每天2次,连续2周。治疗前、后分别做神经功能缺损程度评分并观察患者的在功能性磁共振成像(fMRI)上病灶的影像学的变化。结果观察组治疗2周后的疗效较对照组好(P<0.05);两组患者治疗前、后神经功能评分比较差异有统计学意义(P<0.05)。结论银杏达膜是一种治疗脑梗死的安全有效的药物。

Objective To investigate the clinical effects of Ginkgo Dipyridolum Injection（Xingding Injection） in the treatment of acute cerebral infarction（ACI）.Methods 50 patients with ACI were randomly divided into two groups,25 cases in each group.The control group adopted the routine therapy,while on this basis the observation group was added with Ginkgo Dipyridolum Injection by intravenous drip,twice daily for successive 2 weeks.The neural function deficiency scores were performed and the imageological changes of fMRI were observed before and after treatment in the two groups.Results The effect after 2-week treatment in the observation group was better than that in the control group（P0.05）.The neural function scores before and after treatment showed statistical difference between the two groups（P0.05）.Conclusion Ginkgo Dipyridolum is a safe and effective drug for the treatment of ACI.