高能聚焦超声术与微波消融术治疗持续性变应性鼻炎的疗效观察

The effect observation on high intensity focused ultrasound and microwave ablation for treating persistent allergic rhinitis

目的比较微波消融术与高能聚焦超声术治疗持续性变应性鼻炎(PAR)的疗效。方法选择2009年1月至2010年1月该院收治的PAR患者78例,随机分为两组,治疗组40例,采用高能聚焦超声治疗,对照组38例,采用微波消融术治疗,比较两组患者的治疗效果。结果治疗组治疗后12个月患者的总有效率与对照组比较,差异有统计学意义(P<0.05);术后6、12个月两组患者症状评分比较差异有统计学意义(P<0.05);治疗组治疗后12个月鼻腔黏膜纤毛输送率(MTR)值为(7.31±1.32)mm/min与对照组的(3.26±1.67)mm/min比较,差异有统计学意义(P<0.05)。结论聚焦高能超声治疗经药物、免疫治疗无效且无鼻腔严重解剖结构异常的PAR疗效好,安全。

Objective To compare the effects of microwave ablation and the high intensity focus ultrasound for treating persistent allergic rhinitis（PAR）.Methods 78 cases of PAR treated from January 2009 to January 2010 were selected and randomly divided into two groups.The treatment group（n=40） was treated by the high intensity focused ultrasound and the control group（n=38） was treated by the microwave ablation.The clinical effects were compared between the two groups.Results The total effective rates after 12-month treatment were 97.5% in the treatment group and 94.7% in the control group respectively,difference showing statistical significance（P0.05）.The clinical symptoms scores in postoperative 6,12 months had statistical differences between the two groups（P0.05）.The nasal cavity MTR values after 12-month treatment was（7.31±1.32）mm/min in the treatment group and（3.26±1.67）mm/min in the control group,difference showing statistical significance（P0.05）.Conclusion High intensity focused ultrasound is more effective and safe in treating PAR,which is invalid by medication and immune treatment without nasal serious abnormal anatomical structure.