2,4,5-三氟苯甲酸的合成

Synthesis of 2,4,5-Trifluorobenzoic Acid

以N-苯基四氯邻苯二甲酰亚胺为原料,通过氟代、脱氟、水解、脱羧四步反应制备2,4,5-三氟苯甲酸,含量98.6%,总收率67.7%。该工艺简便、生产成本低、收率高且适合工业化生产。

2,4,5-trifluorobenzoic acid was synthesized from N-phenyltetrachlorophthalimide by fluorination,defluorination,hydrolysis,decarboxylation with a purity of 98.6% and an overall yield of 67.7%.The process is simple,low cost,high yield and suitable for industrial production.