脓毒症免疫干预措施的研究进展

Research Progress on Sepsis and Immune Interventions

脓毒症的发生与机体免疫功能紊乱密切相关。脓毒症早期机体可能表现为失控的持久性炎症反应,晚期则出现免疫抑制,表现为淋巴细胞凋亡,使机体的易感性增加。深入探讨脓毒症免疫干预措施,可为其预防与治疗开拓更广阔的思路与更合理的方案。

The occurrence of sepsis is closely related to the immune dysfunction of the body. During the early period of sepsis, there may be an excessive and constant inflammatory response, and it will be followed by immune depression, demon- strating apoptosis of lymphocytes, which can increase susceptibility of the body. Further investigation of the pathophysiology of the immune dysfunction in sepsis can interpret the mechanism of sepsis and may provide new ideas and more advisable strategies for the prevention and treatment.