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腰椎间盘突出致腰腿疼的病因探讨 被引量:67

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摘要 腰椎间盘突出症疼痛的病因可能是 :以神经根及背根神经节的解剖为基础 ,椎间盘自然或 /和病理退变导致机械压迫为诱因 ,局部炎症 (以 PLA2活性升高为标志 )导致神经根及背根神经节脱髓鞘为条件 ,最终Na+浓度再分布引起异常电活动为根本的必然结果 ,而最终致疼的。这些因素可能是神经根疼机理中不可忽视的重要因素。当然 ,神经根疼的发病机理相当复杂 ,涉及许多生化、免疫、分子生物学和电生理等过程。目前尚无重要的结论性资料阐述根疼的根本原因 ,这有待于进一步的研究。
出处 《颈腰痛杂志》 2000年第3期247-248,共2页 The Journal of Cervicodynia and Lumbodynia
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