磁共振弥散加权成像在肝癌介入治疗疗效评价中的应用进展

Application Advances in Clinical Efficacy Evaluation of DWI in TACE

随着人们生活水平的提高和饮食结构的变化,肝癌的发病率逐年升高,如何提高无法手术治疗的肝癌的疗效一直是研究热点。选择性肝动脉化疗栓塞术是姑息治疗中较为成熟和有效的方法,术后及时随访和准确评价疗效是取得良好疗效的关键。磁共振弥散加权成像(DWI)是目前唯一能在活体组织内进行水分子弥散测量和成像的方法,通过检测组织内水分子运动的状态来反映组织的结构特点,主要应用于神经系统。近年来DWI在腹部脏器的应用也日渐增多,在预测及评价肿瘤疗效的应用上也有了一定的进展。该文总结DWI在肝癌介入术后疗效评价方面的应用现状及进展,以提高对中晚期肝癌治疗的认识。

With the improvement of living standards and changes in the diet structure,the incidence of liver cancer has significantly increased.How to improve the efficacy for inoperable liver cancer has been a research focus.Transcatheter arterial chemoembolization is a more mature and effective method palliative treatment,and timely postoperative follow-up and accurate evaluation of efficacy of surgery are the keys to achieve good efficacy.Diffusion weighted imaging（DWI） is at present the only method which can realize living tissue water diffusion measurement and imaging.The status of the movement of water molecules in the tested tissue can reflect the tissue structure characteristics,mainly used in the nervous system.In recent years the application of DWI in the abdomen also increases,and some progress has been seen in the application of the prediction and evaluation of tumor response.Here is to make a review on the application and progress of DWI in the efficacy evaluation of interventions of hepatic carcinoma,to raise awareness on the treatment of advanced hepaticlular carcinoma.