2型糖尿病患者抑郁患病率及相关因素分析

Depression Prevalence of Type 2 Diabetes Mellitus and the Related Factors

目的探讨2型糖尿病(T2DM)患者抑郁状况及其相关的社会心理因素和生物因素。方法随机选取北京市和平里医院2010年11月至2011年11月就诊的T2DM患者333例,采用Zung抑郁自评量表(SDS),在医师的指导下进行自我抑郁评分。结果 333例患者中,发生抑郁的为123例(36.9%),其中轻度70例,中度46例,重度7例。多因素非条件Logistic回归分析显示文化程度、并发症数、病程、空腹血糖和尿微量白蛋白是T2DM患者伴发抑郁的危险因素,而饮食干预为保护因素。结论 T2DM患者抑郁的发生率较高,与多种社会心理因素相关。及早给予心理指导,使患者在最佳的心理状态下进行治疗,有利于患者各项指标的平稳。

Objective To explore depression status of patients with type 2 diabetes mellitus（T2DM）and its related psychosocial factors and biological factors.Methods 333 cases of patients withT2DM were randomly selected in Beijing Hepingli Hospital from November 2010 to November 2011 as the research objects,and self-depression scores were mesured using the Zung self-rating depression scale（SDS）,under the guidance of a physician.Results Among the 333 patients,the occurrence of depression was seen in 123 patients 36.9%）,including 70 mild cases,46 moderate cases,and 7 severe cases.Multivariate unconditional logistic regression analysis showed that cultural level,number of complications,disease duration,fasting blood sugar level and urinary albumin level were risk factors for incidence of depression in T2DM patients,while diet intervention was a protective factor.Conclusion The incidence of depression in patients with T2DM is high,which is associated with a variety of social and psychological factors.Giving psychological guidance at an early stage,and making the patients treated in the best state of mind will help smoothen the indicators.