急性重症胰腺炎并多器官功能障碍综合征的防治

The Prophylaxis and Treatment of Acute Fatal PancreatitisSupervening Multi-organs Dysfunction Syndrome

目的 :探讨重症胰腺炎并多器官功能障碍综合征(MODS)的防治。方法 :回顾性分析本院1980年2月—2000年2月收治的68例重症胰腺炎患者病例资料。结果 :68例中并发多器官功能障碍综合征28例 ,死亡14例(50%) ,以并发成人呼吸窘迫综合征(ARDS)最高计22例(78 5%)。随受累器官增多 ,死亡率增加。累及器官4个以上 ,死亡率100 %。结论 :急性重症胰腺炎出现ARDS最多 ,早期诊断ARDS并积极调控机体炎症反应 ,预防全身炎症反应综合征(SIRS)向MODS发展。保护重要脏器 ,防止内环境失衡 。

Objective:Treatment strategies and ways were discussed according to the time and symptoms of fatal pancreatitis supervening multi-organs dysfunction syndrome.Methods:The 68 fatal pancreatitis cases were analyzed which were treated in our hospital during 1980 2-2000 2 Results:The average age of this group was 48A.There were 28 cases supervening multi-organs dysfunction syndrome,of which there were 14 cases of death (50%)and 22 cases supervening adult respiratory distress syndrome (ARDS)(78 5%).The death rate was increasing as the more organs were involved.The death rate increased to 100%when more than four organs were involved.Conclusion:The frequency of ARDS in the acute fatal pancreatitis was the highest.In order to prevent the general inflammatory reaction syndrome(GIRS)fron developing into MODS,early diagnose of ARDS and control of organism inflammatory reaction should be done positively.To prevent clinic important organs from injuring and to keep the balance of internal environment is the key to improve the patients with prognosis of fatal pancreatitis.