高龄急性心肌梗塞溶栓治疗的临床评价

Clinical Evaluation of Thrombolytic Treatment in Aged Patients with Acute Myocardial Infarction

目的 :评价高龄急性心肌梗塞患者溶栓治疗的疗效和安全性。方法 :95例发病≤12h的急性心肌梗塞患者中 ,年龄≥70岁34例为高龄组 ,<70岁为低龄组 ,均符合溶栓条件 ,入院后给UK或rSK静脉溶栓 ,120min内观察再通指标 ;记录住院期间心脏事件发生率、病死率、出血并发症。结果 :高龄组与低龄组溶栓治疗后冠状动脉再通率、出血并发症、住院期间病死率无显著性差异(P>0.05) ,心脏事件中高龄组发生率高于低龄组。结论 :高龄急性心肌梗塞患者若无其他明确禁忌症 。

Objective:To evaluate the efficacy and safety of thrombolytic treatment in aged patients with acute myocardial infarction(AMI).Methods:95 cases of AMI (onset<12 hour)were divided into two groups,the aged group(>70 year old)and the control group(<70 year old),which conformed to thrombolytic condition.After admitted to hospital,UK or rSK was intravenously infused and the reperfusion criteria were observed during 120 minutes.The incidence of cardiac attack,mortality rates and hemorrhagic complications were recorded during hospitalization.Results:After thrombolytic treatment,the reperfusion rate of coronary artery,hemorrhagic complications and the mortality rate were not significantly statistically different in the aged group and the control group(P<0.05).The incidence of cardiac attack was higher in the aged group than that of the control group.Conclusion:The thrombolytic treatmnent was safe and effective in aged patients with AMI.