期刊文献+

慢性乙型肝炎患者血清IL-8和IL-23检测的临床意义

下载PDF
导出
摘要 目的探讨慢性乙型肝炎患者血清IL-8和IL-23水平的变化。方法:应用双抗体夹心酶联免疫吸附法(ELISA)对43例慢性乙型肝炎患者进行了血清IL-8、IL-23水平检测,并与36名正常人作比较。结果慢性乙型肝炎患者血清IL-8和IL-23水平均高于正常组(P〈0.01),且IL-8和IL-23呈明显的正相关(P〈0.01)。结论慢性乙型肝炎患者血清IL-8和IL-23水平检测对疾病的诊断和治疗是-个有用的临床指标。
出处 《淮海医药》 CAS 2013年第2期143-144,共2页 Journal of Huaihai Medicine
  • 相关文献

参考文献8

  • 1Chu YK, Wu JS, Ma Q J, et al. Plasma TNF levels during the forma- tion of liver cirrhosis and portal hypertension in rat[ J]. Huaren Xi- aohua Zazhi, 1998,6 ( 9 ) : 755-756.
  • 2Chinese Medical Association 5th National conference of infectious and parasitic disease protecting progyam of hepatitis (in progress) [ J ]. Zhonghua Chuanranbing Zazhi, 1995,13 (2) :241 - 246.
  • 3唐星火,卢东红.乙肝相关疾病患者血清HBV DNA和IL-6、IL-8水平分析[J].胃肠病学和肝病学杂志,2007,16(6):546-547. 被引量:13
  • 4Oppmann B, Lesley R, Blom B, et al. Novel p19 protein engages IL- 12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 [ J ]. Immunity, 2000,13 ( 5 ) :715-725.
  • 5杨帆,伍伟锋.白细胞介素-23在小鼠病毒性心肌炎中的表达[J].临床心血管病杂志,2011,27(2):102-104. 被引量:3
  • 6Fitch E, Harper E, Skorcheva I. Pathophysiology of psoriasis: recent advance on IL-23 and Thl7 cytokines [ J ]. Curr Rheumatol Rep, 2007,9(6) :461-467.
  • 7Wong CK, Lit LCW, Tam LS, et al. Hyper-production of IL-23 and IL-27 in patients with systemic lupus erythematosus:Implications for Thl7-mediated inflammation in autoimmunity [ J]. Clin Immunol, 2008,127 ( 3 ) : 385-393.
  • 8Krakauer M, Sorensen P, Khadem IM, et al. Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis: interferon- 13treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression [ J ]. Mult Scler,2008,14 ( 5 ) : 622 -630.

二级参考文献19

  • 1病毒性肝炎防治方案(试行)[J].中华传染病杂志,1995,13(4):241-247. 被引量:1767
  • 2梅小平,敬雪明,李健,常茂华,曾跃.乙型肝炎患者血清IL-6、IL-8、TNF-α水平与肝损程度、HBVDNA含量的相关性分析[J].中国现代医学杂志,2006,16(3):395-397. 被引量:22
  • 3YAJIMA T,KNOWLTON K U.Viral myocarditis:from the perspective of the virus[J].Circulation,2009,119:2615-2624.
  • 4CASTELLANO G,AFFUSO F,DI CONZA P,et al.Myocarditis and dilated cardiomyopathy:possible connections and treatments[J].J Cardiovasc Med,2008,9:666-671.
  • 5PARK H,LI Z,YANG X O,et al.A distinct lieage of CD4+T cells regulates tissue inflammation by producing interleukin 17[J].Nat Immunol,2005,6:1133-1141.
  • 6OPPMANN B,LESLEY R,BLOM B,et al.Novel p19 protein engages IL-12p40 to form a cytokine,IL-23,with biological activities similar as well as distinct from IL-12[J].Immunity,2000,13:715-725.
  • 7FITCH E,HARPER E,SKORCHEVA I.Pathophysiology of psoriasis:recent advances on IL-23 and Th17 cytokines[J].Curr Rheumatol Rep,2007,9:461-467.
  • 8WONG C K,LIT L C W,TAM L S,et al.Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus:Implications for Th17-mediated inflammation in autoimmunity[J].Clin Immunol,2008,127:385-393.
  • 9KRAKAUER M,SORENSEN P,KHADEMI M,et al.Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis:interferon-β treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression[J].Mult Scler,2008,14:622-630.
  • 10LANGRISH C L,CHEN Y,BLUMENSCHEIN W M,et al.IL-23 drives a pathogenic T cell population that induces autoimmune inflammation[J].J Exp Med,2005,201:233-240.

共引文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部