不规则抗体48480例筛查结果分析

Analysis on screening results of 48 480 cases of irregular antibodies

目的探讨不规则抗体筛查在临床输血中的意义。方法用强生全自动血型分析仪对2011年5～12月的输血标本进行不规则抗体筛选,阳性标本进一步做抗体鉴定,同时查阅2006年1月至2011年4月的不规则抗体筛查结果及患者相关信息。结果 48 480例输血申请者中,不规则抗体阳性297例,阳性率为0.61%。结论不规则抗体筛查能有效降低或避免溶血性输血反应的发生,保证输血安全,尤其对输血史和妊娠史患者非常重要。

Objective To explore the significance of screening and detecting irregular antibodies in clinical blood transfusion. Methods The autovue Irnova automatic blood group analyzer was used for screening irregular an- tibodies in the patients with blood transfusion from May 2011 to December 2011. Those positive samples were per- formed the further antibody identification. At the same time, the irregular antibody screening results from January 2006 to April 2011 and the patients＇ related information were consulted. Results There were 297 positive samples of irregular antibodies in 48 480 patients applying for blood transfusion. The positive rate was 0. 61%. Conclusion Screening irregular antibodies can effectively reduce the incidence of hemolytic transfusion reaction and ensure the blood transfusion safety, which is especially important for the patients with the history of blood transfusion or preg- nancy.