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VEGF、IGF-Ⅰ和f-PSA联检在前列腺癌诊断中的临床意义 被引量:4

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摘要 本文通过检测血清中血管内皮生长因子(VEGF)、胰岛素样生长因子Ⅰ(IGF-Ⅰ)、游离前列腺特异性抗原(f-PSA)的水平,探讨其组合检测对前列腺癌(Pca)的临床诊断价值. 1 材料和方法 1.1 对象 本院2010年3月~2012年6月泌尿科住院患者,其中Pca患者65例,年龄(53~90)岁,平均70.6岁;前列腺增生(BPH)患者54例,年龄(57~86)岁,平均67.3岁,所有病例组均经前列腺多点穿刺活检或术后病理切片确诊.健康对照组52名,年龄(61~82)岁,平均69岁,均来自本院体检中心作健康检查正常的老年人,血尿常规、肝肾功能等生化指标均在正常参考范围,既往无心肺等重要脏器疾患,无BPH等相关疾病(无自觉症状,直肠指检及B超检查均无异常.
作者 孙玲芬 张瑾
出处 《放射免疫学杂志》 CAS 2013年第2期212-213,共2页 Journal of Radioimmanology
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参考文献4

  • 1Bronislaw P, Jeremy G, Kris P, et al. Complete and specific inhibi- tion of adult lymphatic regeneration by a novel VEGFR-3 neutralizing anti- body[ J]. J Nail Cancer Inst ,2005,97 ( 1 ) : 14-21.
  • 2沈百欣,钱立新,张炜,杨杰,宋宁宏,张杰秀,邵鹏飞,徐郑,虞梅林,王震,王心如.VEGF和VEGF-C表达增加与前列腺癌进展的相关性研究[J].中华泌尿外科杂志,2006,27(S2):42-46. 被引量:7
  • 3Kawada M, Inoue H, Masuda T, et al . Insulin-like growth factor 1 serected from prostate stromal cells mediates tumor-stromal cell interac- tions of prostate cancer[ J]. Cancer Res ,2006,66 (8) :4419-4425.
  • 4Raddam AW, Allen NE , Appleby P, et al. Insulin-like growth fac- tors ,their binding proteins,and prostate cancer risk :analysis of individual patient data from 12 prospective studies [ J ]. Ann Intern Med, 2008,149 (7) :461-471.

二级参考文献19

  • 1Brian Nicholson,,Dan Theodorescu.Angiogenesis and prostate canc-er tumor growth. Journal of Cellular Biochemistry . 2004
  • 2Daneshmand S,Quek ML,Stein JP,et al.Prognosis of patients with lymph node positive prostate cancer following radical prostatec-tomy:Longterm results. Journal d Urologie . 2004
  • 3Baltaci S,Orhan D,Gogus C,et al.Inducible nitric oxide synthase expression in benign prostatic hyperplasia,low-and high-grade pros-tatic intraepithelial neoplasia and prostatic carcinoma. BJU International . 2001
  • 4Ichinoe M,Mikami T,Shiraishi H,et al.High microvascular densi-ty is correlated with high VEGF,iNOS and COX-2expression in penetrating growth-type early gastric carcinomas. Histopathology . 2004
  • 5Carrol PR,Lee KL,Fuks ZY,et al.Cancer of the prostate. Cancer:principles and practice of oncology . 2001
  • 6Stefanou D,,Batistatou A,Kamina S,et al.Expression of vascular endothelial growth factor(VEGF)and association with microvessel density in benign prostatic hyperplasia and prostate cancer. In Vivo . 2004
  • 7Kollermann J,Helpap B.Expression of vascular endothelial growth factor(VEGF)and VEGF receptor Flk-1in benign,premalignant,and malignant prostate tissue. American Journal of Clinical Pathology . 2001
  • 8Niki T,Iba S,Tokunou M,et al.Expression of vascular endothelial growth factors A,B,C,and D and their relationships to lymph node status in lung adenocarcinoma. Clinical Cancer Research . 2000
  • 9Oh SJ,Jeltsch MM,Birkenhager R,McCarthy JE,Weich HA,Christ B,Alitalo K,Wilting J.VEGF and VEGF-C:Specific in-duction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. Developmental Biology . 1997
  • 10Kriehuber E,Breiteneder-Geleff S,Groeger M,et al.Isolation and characterization of dermal lymphatic and blood endothelial cells re-veal stable and functionally specialized cell lineages. The Journal of Experimental Medicine . 2001

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