儿童重症手足口病不同病情阶段视频脑电图特征与临床(附48例报告)

THE CLINICAL AND VIDEO-EEG FEATURES ON CHILDREN WITH SEVERE HAND-FOOT-MOUTH DISEASE IN DIFFERENT DISEASE STAGES ( A REPORT OF 48 CASES )

目的:探讨分析重症儿童手足口病(HFMD)不同病情阶段视频脑电图(VEEG)的特征。方法:对48例重症HFMD患儿的VEEG进行了回顾性分析。结果:发展期,48例患儿VEEG均有异常,异常度与脑炎改变基本符合,与临床表现不完全一致,一般以背景慢波及额颞区的放电为主要特征,重度VEEG异常者变化各异;好转期大多数患儿背景逐渐恢复,浅睡期额颞区出现散在的尖(棘),尖慢(棘慢)波;康复期重度VEEG异常恢复慢,残留局灶或多灶性放电及背景慢波。结论:掌握HFMD不同病情阶段的VEEG特征,对病情的治疗、康复起到了重要的指导作用。

Objective：To analyse clinical and VEEG features on children with severe hand-foot-mouth disease in different disease stages. Methods： The VEEG were analyzed retrospectively in 48 patients with severe HFMD. Results： In development stage,VEEG of 48 cases were all abnormal, abnormal degree and change of encephalitis were basieall consistent, but and clinical manifestations were not completely consistent, generally, background of slow wave and the discharge of frontal and temporal region w^re main feature. Severe abnormal VEEG was varietyl In improvement stage, background of most cases was gradually recovered. In shallow sleep period, frontal and temporal areas appear scattered sharp （ spike ） , sharp （ spike ） and slow wave.In rehabilitation stage, severe abnormal VEEG was recovered slowly, with residual focal or multifocal discharge and the background of slow wave. Conclusion： Mastering VEEG features of HFMD in different stages of diseases was of important guiding role in treatment of the disease and rehabilitation.