南京市10691例妇女宫颈疾病筛查情况分析

Analysis of cervical diseases in 10 691 women in Nanjing city

目的了解南京地区宫颈病变发生情况并探讨三阶梯技术在妇女宫颈疾病筛查中的应用价值。方法采用宫颈液基细胞检测技术、核酸分子快速导流杂交基因芯片技术及阴道镜检查的方法对2012年1-8月在南京市妇幼保健院进行妇女病普查共10691例病例资料进行回顾性分析,检测宫颈癌前病变的发生情况及与各致病因素的关系。结果普查发现TCT结果异常278例,并通过阴道镜下宫颈活检确诊宫颈上皮内瘤变(CIN)Ⅰ15例,CINⅡ16例,CINⅢ5例,30～49岁育龄女性为高发人群,宫颈癌前病变患者HPV16感染率最高(20.12%)。结论三阶梯技术的应用可有效筛查妇女宫颈疾病并提高早期诊断率,其发病情况与年龄及HPV感染有关。

Objective To study the occurrence of cervical diseases and the three step technique in women with cervical disease screening value. Methods Clinical data of 10 691 women attending Gynecological examination in Maternal and Child Health Care Hospital between Jan to Aug 2012 were retrospectively studied. These included the data obtained from the cervical liquid- based cell detection method, the rapid flow-through hybridization of nucleic acid molecules gene chip method, and eolposeopy. Results The three step technology confirmed CIN 15 patients, CIN Ⅱ16 patients and CINIⅡ 5 patients. Conclusion Three step technology can effectively screening women with cervical diseases and improve the early diagnosis rate.