五华县60例HBsAg阳性携带者转归及其家庭成员乙肝感染调查结果分析

Analysis on outcome of 60 cases of HBsAg positive carriers and HBV infection among their family members in Wuhua county

目的了解五华县HBsAg阳性携带者转归及其家庭成员HBV感染情况。方法对在2006年血清学调查中发现的60例HBsAg阳性携带者及其家庭成员进行肝功能及HBV相关指标检测,并进行分类诊断。结果 60例HBsAg阳性携带者3年后分类诊断为HBsAg阴转5例(8.33%),HBV携带者47例(78.33%),慢性乙肝7例(11.67%),肝细胞癌1例(1.67%)。检测其家庭成员126人,检出HBsAg阳性25人,阳性率19.84%,分类诊断为HBV携带者21例(84.00%),慢性乙肝4例(16.00%)。结论 HBsAg阳性携带者家庭成员HBsAg阳性率高于普通人员。

Objective To investigate the outcome of HBsAg positive carriers and status of HBV infection among their family members in Wuhua county, and provide the scientific basis for control and prevention of hepatitis B. Methods Among the 60 cases of HBsAg positive carriers and their family members were examined for liver function and HBV index, and performed classification diagnosis. Results 60 cases of HBsAg positive carriers found in 2006 serological survey were examined.The results showed HBsAg positive carriers after 3 years, 5 cases （8.33%） were converted HBsAg negative, 47 cases （78.33%） HBV carriers, 7 cases （ll.67%）chronic hepatitis B, 1 case （1.67%） HCC. Among 126 family members who lived together with these patients, 25 cases were HBsAg positive, with a positive rate of 19.84%, 21 cases （84.00%） HBV carriers, and 4 cases （16.00%） chronic hepatitis B. Conclusion It is necessary to carry out the regular examination for HBsAg positive carriers and their family members.