子宫颈微偏腺癌1例报道及文献回顾

Minimal deviation adenocarcinoma of the cervix:case report and literature review

目的:报道1例子宫颈微偏腺癌病例,探讨其临床病理学特征。方法:对1例子宫颈微偏腺癌进行临床病理学及免疫组化观察。结果:显微镜下,腺体由分泌黏液的柱状上皮构成,腺体扭曲,外形不规则,大多数腺体与正常腺体无法区别,少部分腺体的细胞核有中度不典型增生,核分裂象可见。结论:子宫颈微偏腺癌是一种少见的高分化黏液腺癌,临床诊断应排除良性腺体增生及内膜异位。因大多数病例子宫颈活检不能诊断,所以在日常临床工作中如遇到考虑恶性肿瘤,而镜检为良性时,应考虑子宫颈微偏腺癌,腺体浸润深度是诊断的关键。

Objective：To report a case of minimal deviation adenocarcinoma of the cervix, and explore its clinical and pathological features. Methods：The histopathological and immunohistochemical findings of a case of minimal deviation adenocarcinoma of the cervix were observed. Results：Microscopically, glandular organ was set up by mucilaginous of the columnar epithelium, glandular organ squirmed, irregular shape, most of the glandular organs can not distinguish between the normal glandular organ, occasionally, some glandular organs＇ nucleus had midrange atypical hyperplasia, infiltration depth of the glandular organ is the key for diagnosis. Conclusion： Minimal deviation adenocarcinoma of the cervix is a rare well - differentiated mucinous ad Clinical diagnosis should rule out ectopic benign glandular hyperplasia and adenomyosis. Because the majority of cases of cervical biopsy can not be diagnosed, in routine clinical work,clinical considerations in case of malignancy, while the microscopic examination as benign should be considered minimal deviation adenocarcinoma of the cervix.